LGE Provides Incremental Prognostic Information Over Serum Biomarkers in AL Cardiac Amyloidosis
نویسندگان
چکیده
منابع مشابه
Delayed hyper-enhancement magnetic resonance imaging provides incremental diagnostic and prognostic utility in suspected cardiac amyloidosis.
OBJECTIVES We sought to assess the diagnostic accuracy and incremental prognostic value of delayed hyper-enhancement cardiac magnetic resonance (DHE-CMR) compared with electrocardiographic and transthoracic echocardiographic (TTE) parameters in such patients. BACKGROUND Utility of DHE-CMR in the diagnosis of patients with suspected cardiac amyloidosis (CA) has recently been demonstrated, but ...
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Background Cardiac Amyloidosis (CA) is an important prognostic indicator in patients with systemic amyloidosis. Cardiac MRI has emerged as imaging modality of choice to evaluate patients with CA. Delayed hyper-enhancement cardiac magnetic resonance (DHE-CMR) provides incremental diagnostic and prognostic utility in suspected CA. We performed a meta-analysis to evaluate the prognostic role of LG...
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BACKGROUND The prognosis and treatment of the 2 main types of cardiac amyloidosis, immunoglobulin light chain (AL) and transthyretin (ATTR) amyloidosis, are substantially influenced by cardiac involvement. Cardiovascular magnetic resonance with late gadolinium enhancement (LGE) is a reference standard for the diagnosis of cardiac amyloidosis, but its potential for stratifying risk is unknown. ...
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Background Transthyretin amyloidosis (ATTR amyloidosis) is an under diagnosed cause of heart failure with no truly quantitative test. Cardiac involvement is the leading cause of death and influences therapeutic choices. Since new therapies are imminent which aim to treat ATTR amyloidosis the lack of a quantitative test represents a critical step for drug development. In cardiac AL amyloidosis, ...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Imaging
سال: 2016
ISSN: 1936-878X
DOI: 10.1016/j.jcmg.2015.10.027